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Hemibrain — Drosophila central brain connectome (~25k neurons) 3D

FIB-SEM connectomics · Drosophila melanogaster · Brain

Hemibrain — Drosophila central brain connectome (~25k neurons) Open in viewer ▶

⚠ Very large dataset (~25,000 neurons). Please read the viewer guide first — view the whole set zoomed out, then enable Overview before zooming into detail.

The Janelia FlyEM Hemibrain v1.2.1 connectome — a dense FIB-SEM reconstruction of a large portion of the adult Drosophila melanogaster central brain (Scheffer et al. 2020), one of the foundational fly connectomes. This scene is 25,000 reconstructed neurons (the largest traced bodies), each a full-resolution surface mesh served as a u16-quantized meshopt (q14) 3D-Tiles octree and tagged with neuPrint metadata: cell type, instance name, traced status, pre/post synapse counts, and dominant neuropil region. Each neuron is colored individually; use "Color By" Cell Type / Primary ROI to read the brain's organization. At 25k dense neurons it is a heavy volume — use the viewer's filter / Force-Zoom coarse LOD to explore subsets and regions.

Metadata

features25,000 meshes
zoom0–4
tiles3,233

Provenance & reproducibility

Source: https://www.janelia.org/project-team/flyem/hemibrain
License: CC BY 4.0
Cite: Scheffer LK, et al. A connectome and analysis of the adult Drosophila central brain. eLife 9:e57443 (2020). Janelia FlyEM Hemibrain v1.2.1, CC BY 4.0.

download_hemibrain.py --streaming --tile --max-neurons 25000 --max-zoom 4 --compression meshopt-q14 (25,000 largest traced neurons; meshes via cloud-volume from gs://neuroglancer-janelia-flyem-hemibrain; metadata via neuPrint hemibrain:v1.2.1; u16-quantized meshopt GLB 3D-Tiles octree; features indexed uniquely per body_id)
muDM: neuron surfaces → TIN (featureClass = cell type); per-neuron color by body_id (hash); tags: cell_type, instance, status, pre/post, primary_roi

Downloads

Programmatic access

3D Tiles entry point:

https://ngrf.mudm.io/tiles/hemibrain/tileset.json

Machine descriptors: tilejson.json · croissant.json · full access guide